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The fifth-year residents return for the first day of a year that will make or break their careers: Meredith faces the consequences of tampering with Derek's clinical trial and is terminated at the hospital| April tries to step up to the plate as Chief Resident in the wake of a giant sinkhole in the middle of Seattle| and Cristina and Owen are still at odds over their drasticall...。南方某市法院开庭审理了一起毒杀案，被告人蒋漫枝（钟欣潼饰）涉嫌用河豚毒素杀害其丈夫柳慕阳（张睿饰）。辩护人栾珠（蒙亭宜饰）坚称柳慕阳是自己误食了毒酸奶而非预谋杀害，此时另一条线索表明，八年前的一起强奸案，被害人就是如今的蒋漫枝，而强奸犯许一城竟然和被害者柳慕阳长得一模一样，千丝万缕的联系预示着这两起案件远没有那么简单。蒋漫枝为何会爱上曾性侵过自己的人，她又为何会再次痛下杀手？。宁凡遭火灾家破人亡，被救后成药神创非凡集团，误认恩人为张丽丽并入赘。五年后，张氏集团将上市，宁凡备五百亿合同为妻庆生，但妻心系他人致女摔伤成植物人。张丽丽与高世杰争病房，宁凡对妻彻底失望愤怒。。